Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/86864
Title: A composite risk assessment model to screen for gestational diabetes mellitus among Mediterranean women
Authors: Savona-Ventura, Charles
Vassallo, Josanne
Marre, Michel
Karamanos, Basil G.
Authors: MGSD-GDM Study Group
Keywords: Diabetes in pregnancy -- Mediterranean Region
Glucose tolerance tests
Diabetes -- Risk factors
Diabetes -- Diagnosis
Issue Date: 2013
Publisher: John Wiley & Sons, Inc.
Citation: Savona-Ventura, C., Vassallo, J., Marre, M., & Karamanos, B. G. (2013). A composite risk assessment model to screen for gestational diabetes mellitus among Mediterranean women. International Journal of Gynecology & Obstetrics, 120(3), 240-244.
Abstract: OBJECTIVE: To determine whether clinical risk assessment for gestational diabetes mellitus (GDM) may preclude the need for universal screening with an oral glucose tolerance test (OGTT) in situations of economic restraint.
METHODS: Women with either GDM (n = 119) or normal glucose tolerance (n = 1249) were recruited from centers among 11 Mediterranean countries between August 1, 2010, and May 31, 2011. Outcome measures included anthropomorphic and biological data, obstetric outcomes, and infant outcomes.
RESULTS: Significant risk factors for GDM included maternal age of 30 years or more; elevated body mass index (BMI, calculated as weight in kilograms divided by the square of height in meters); elevated diastolic blood pressure; previous history of macrosomia; and family history of diabetes mellitus. These factors each had high specificity but low sensitivity for predicting GDM; however, when used in combination, sensitivity increased but specificity fell. Fasting blood glucose (FBG) level had high sensitivity (73.9%) and specificity (90.2%) for predicting GDM. Sensitivity was further increased by combining FBG measurement with maternal age and BMI (96.6%).
CONCLUSION: Use of a composite model to prescreen women for GDM risk may reduce the need for universal screening with the OGTT among centers facing health-cost pressures.
URI: https://www.um.edu.mt/library/oar/handle/123456789/86864
Appears in Collections:Scholarly Works - FacM&SMed

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