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Title: A case of neuroleptic malignant syndrome on withdrawal of benzhexol
Authors: Lofaro, Thomas
Falzon, Stephanie
Ferry, Peter
Keywords: Neuroleptic malignant syndrome -- Malta -- Case studies
Parkinson's disease -- Treatment
Cholinergic antagonists -- Therapeutic use
Issue Date: 2010
Publisher: Malta Medical Journal
Citation: Malta Medical Journal. 2010, Vol.22(2), p. 32-33
Abstract: The neuroleptic malignant syndrome is a rare and potentially lethal reaction which is usually associated with the use of medications with antidopaminergic properties. This article describes the case of an elderly gentleman who developed the neuroleptic malignant syndrome after withdrawal of the anticholinergic agent benzhexol (trihexyphenidyl hydrochloride), which he was taking for Parkinson’s disease. The patient improved rapidly after treatment was restarted. This case adds to the evidence that antidopaminergic agents may not be necessary for the development of this syndrome, and increased awareness of this possibility is advisable in such circumstances.
Appears in Collections:MMJ, Volume 22, Issue 2
MMJ, Volume 22, Issue 2
Scholarly Works - FacM&SMed
Scholarly Works - FacSoWGer

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