Please use this identifier to cite or link to this item:
https://www.um.edu.mt/library/oar/handle/123456789/93233| Title: | A mutation in the LRP4 gene is associated with bone mineral density in Maltese postmenopausal women |
| Authors: | Formosa, Melissa Marie Borg, Joseph J. Bezzina Wettinger, Stephanie Farrugia, Rosienne Xuereb-Anastasi, Angela |
| Keywords: | Osteoporosis -- Genetic aspects Bone density Osteoporosis in women -- Malta |
| Issue Date: | 2014-05 |
| Publisher: | Springer Nature Limited |
| Citation: | Formosa, M. M., Borg, J., Bezzina-Wettinger, S., Farrugia, R., & Xuereb-Anastasi, A. (2014). A mutation in the LRP4 gene is associated with bone mineral density in Maltese postmenopausal women. European Journal of Human Genetics, 22(s1), 97. |
| Abstract: | BACKGROUND: Osteoporosis is a hereditary multifactorial skeletal disease
characterised by low bone mass and increased fracture susceptibility. The
low-density lipoprotein receptor-related protein 4 (LRP4) controls the actions of sclerostin which is a known inhibitor of the Wingless (Wnt)/Beta
(β) catenin pathway involved in bone formation. OBJECTIVE: To evaluate the effect of two non-synonymous coding polymorphisms rs6485702 (A>G) and rs2306033 (C>T) in relation to Bone Mineral Density (BMD) and different low-trauma fractures in Maltese postmenopausal women. [excerpt] |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/93233 |
| Appears in Collections: | Scholarly Works - FacHScABS |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| ESHG2014Abstracts1-99.pdf Restricted Access | 387.45 kB | Adobe PDF | View/Open Request a copy |
Items in OAR@UM are protected by copyright, with all rights reserved, unless otherwise indicated.