| CODE | CPH5301 | |||||||||
| TITLE | Molecular and Receptor Pharmacology | |||||||||
| UM LEVEL | 05 - Postgraduate Modular Diploma or Degree Course | |||||||||
| MQF LEVEL | 7 | |||||||||
| ECTS CREDITS | 6 | |||||||||
| DEPARTMENT | Clinical Pharmacology and Therapeutics | |||||||||
| DESCRIPTION | Learning Objectives This study-unit will provide a clear understanding of pharmacological processes occurring at a cellular and molecular level. It will cover the principles of how drugs interact with molecular processes at a receptor level and elicit cellular responses. The student will learn how new developments in this area are being used in the development on pharmacological leads in new drug development. Study-unit aims: This study-unit will: - Provide a sound understanding of the principles underlying cellular and molecular pharmacology; - Explain the advances in the classification of drug receptors; - Receptor structures and conformations; - Signal transduction pathways; - Control of receptor expression and modulators of receptor function; - Discuss the advances in experimental molecular pharmacology and experimental approaches to studying receptor function; - Discuss the applications of genetics in pharmacotherapy; - DNA polymorphisms and pharmacological responses; - Gene-based therapy. Learning Outcomes: 1. Knowledge & Understanding By the end of this study-unit, the student will be able to: - Apply approaches in molecular pharmacology to study receptor function; - Understand how advances in the understanding of receptor structures and conformations, signal transduction pathways and modulators of receptor function can lead to novel pharmacological therapy; - Apply genetic principles in pharmacotherapy. 2. Skills By the end of this study-unit, the student will be able to: - Apply correct principles in molecular pharmacology to develop novel drug therapy; - Understand how an understanding of receptor functions are used in the drug development and clinical setting; - Explain how DNA polymorphisms and pharmacological responses are used in pursuing different aspects of genetics in pharmacotherapy. Main texts: Recommended • Brooks G (Editor).Gene Therapy: The Use of DNA as a Drug. Pharmaceutical Press • Terry Kenakin, Molecular Pharmacology: A Short Course. 2010 • Martin Zdanowicz, Concepts in Pharmacogenomics, 2010 |
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| STUDY-UNIT TYPE | Lecture | |||||||||
| METHOD OF ASSESSMENT |
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| LECTURER/S | Duncan Ayers John Joseph Borg Marisa Cassar Anthony Fenech Godfrey Grech |
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The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints. Units not attracting a sufficient number of registrations may be withdrawn without notice. It should be noted that all the information in the description above applies to study-units available during the academic year 2023/4. It may be subject to change in subsequent years. |
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