Study-Unit Description

Study-Unit Description


TITLE Advances in Clinical Pharmacology and Toxicology

LEVEL 05 - Postgraduate Modular Diploma or Degree Course


DEPARTMENT Clinical Pharmacology and Therapeutics

DESCRIPTION This study-unit will discuss advances and developments in clinical pharmacology and toxicology. Through this unit students will have the opportunity to develop an understanding of various drugs in specific medical conditions and in individualized drug prescribing. The application of clinical pharmacological principles for optimising regimens for the individual patient will be discussed for specific drug classes.

Study-unit aims:

This study-unit will provide a moderated forum for discussion on developments in various aspects of pharmacology. Through this unit students will have the opportunity to assess novel knowledge in pharmacology and the use of drugs in various clinical conditions. The topics covered will include:
- Medicines Regulation
- Principles of pharmacokinetics and pharmacodynamics
- Drugs used in neurological disorders
- Drugs used in the treatment of allergies and dverse drug reactions
- Antimicrobial agents
- Drugs used in respiratory disorders
- Glucocorticoids
- Antihypertensive, diuretics and Antiarrhythmic drugs
- Analgesics
- Antidiabetic agents
- Anti cancer drugs and immunotherapy
- Drugs acting on Endocrine system
- Drugs acting on the GI tract
- Drugs used in Obstetrics and gynaecology
- Drugs used in the management of anaemias
- Toxicology and poisoning

Learning Outcomes:

1. Knowledge & Understanding
By the end of this study-unit, the student will be able to:
- understand various aspects of developments in clinical pharmacology.
- assess use of drugs in various medical conditions
- understand clinical pharmacological and toxicological principles of various drug classes

2. Skills
By the end of this study-unit, the student will be able to:
- Apply knowledge of the clinical pharmacology of drugs to understanding new developments in clinical scenarios
- Apply scientific pharmacological principles in clinical situations
- Explain concepts in scientific published articles which refer to differing drug therapies

Main texts:

- Humphrey P. Rang HP, Dale MM, Ritter JM, Flower R. Rang & Dale's Pharmacology. Churchill Livingstone. 6th Ed.
- Grahame-Smith D, Aronson J. Oxford Textbook of Clinical Pharmacology and Drug Therapy. Oxford University Press. 3rd Ed.
- Bennett PN, Brown MJ. Clinical Pharmacology. Churchill Livingstone. 10th Ed.
- British National Formulary. Pharmaceutical Press.

- Brunton L, Lazo J, Parker K. Goodman & Gilman's The Pharmacological Basis of Therapeutics. McGraw-Hill Medical. 11th Ed.
- Waller DG, Renwick AG, Hillier K. Medical Pharmacology and Therapeutics. Saunders. 3rd Ed.

Lecture notes
- Reid JL, Rubin PC, Walters MW. Clinical Pharmacology and Therapeutics (Lecture Notes). Blackwell. 7th Ed.
- Neal MJ. Medical Pharmacology at a Glance. Wiley-Blackwell. 6th Ed.

ADDITIONAL NOTES Pre-requisite Study-units: CPH5301, CPH5302, CPH5303.

STUDY-UNIT TYPE Lecture, Tutorial and Practical

Assessment Component/s Resit Availability Weighting
Assignment Yes 50%
Examination (2 Hours) Yes 50%

LECTURER/S Duncan Ayers
Christopher Barbara
Maria A. Cordina (Co-ord.)
Paul Cuschieri
Roger Ellul Micallef
Frederick F. Fenech
Helen Mc Clay
Janet Mifsud
Yves Muscat Baron
Charles Scerri
Doriette Soler
Patricia Vella Bonanno

The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints.
Units not attracting a sufficient number of registrations may be withdrawn without notice.
It should be noted that all the information in the study-unit description above applies to the academic year 2018/9, if study-unit is available during this academic year, and may be subject to change in subsequent years.