Professor Jean Calleja-Agius graduated as a Doctor of Medicine and Surgery from the University of Malta in 1999. She further specialised in Obstetrics and Gynaecology, both locally and at University College London Hospital (UCLH). She obtained her Memberships of the Royal College of Obstetricians and Gynaecologists and of the Royal College of Physicians of Ireland, on her first attempt in 2005. From an early stage in her career, Professor Calleja-Agius showed a keen interest in research and teaching on all aspects of anatomy, particularly embryology and reproductive sciences. She was appointed as Assistant Lecturer in 2000, and since then has been teaching medical students, post-graduate trainees and other health professionals. She organised the first Advanced Life Support in Obstetrics (ALSO) UK in Malta in July 2011 for training obstetricians and midwives. She obtained a distinction in her MSc in Clinical Embryology at the University of Leeds, under the supervision of Prof Helen Picton. She has numerous peer-reviewed research articles published in international high impact journals. She obtained her PhD (without corrections) at University College London (UCL) in February 2012. The title of her thesis is 'The Role of Pro- and Anti-inflammatory Cytokines in Early Pregnancy'. Her research involved investigation of the association between systemic and placental cytokines and miscarriages in human pregnancy. Her research supervisors were Professor Eric Jauniaux (UCL) and Dr Shanthi Muttukrishna (UCL/UCC), and the PhD examiners were Prof Lesley Regan from Imperial College (London) and Prof Siobhan Quenby from University of Warwick, who are all world authorities in the field of miscarriages and pregnancy complications. The current research interests of Prof Calleja-Agius are embryology and reproductive medicine, particularly recurrent miscarriages and infertility.
Prizes: 2012: Best Abstract, 15th ISGE Congress, Florence 2010: Best Abstract in Under-34 Competition, 14th ISGE Congress, Florence 2009: Green Armytage Travel Bursary (RCOG) 2008: Overseas Fund Travel Award (RCOG) 2007: Travel Award for the 31st British International Congress of Obstetrics and Gynaecology 2006: Ethicon Travel Award (RCOG) 2005: Chancellor's Award (UOM) 2003: Best Oral Presentation 5th Maltese Medical School Conference
Other Publications: Calleja-Agius J, Jauniaux E, Muttukrishna S. Placental Villous Expression of TNFÎ± and IL-10 and Effect of Oxygen Tension in Euploid Early Pregnancy Failure. American Journal of Reproductive Immunology. 2012 Jun; 67(6):515-25. Epub 2012 Jan 16
Calleja-Agius J, Jauniaux E, Pizzey AR, Muttukrishna S. Investigation of systemic inflammatory response in first trimester pregnancy failure. Human Reproduction. 2012 Feb;27(2):349-57.
Calleja-Agius J, Jauniaux E, Muttukrishna S. Inflammatory cytokines in maternal circulation and placenta of chromosomally abnormal first trimester miscarriages. Clincal and Developmental Immunology. 2012;2012:175041.
Calleja-Agius J, Mallia P, Sapiano K, Schembri-Wismayer P. A review of the management of intersex. Neonatal Network. 2012 Mar-Apr;31(2):97-103.
Portelli M, Pollacco J, Sacco K, Schembri-Wismayer P, Calleja-Agius J. Endometrial seedlings. A survival instinct? Immunomodulation and its role in the pathophysiology of endometriosis. Minerva Ginecologica. 2011 Dec;63(6):563-70.
Sacco K, Portelli M, Pollacco J, Schembri-Wismayer P, Calleja-Agius J. The role of prostaglandin E(2) in endometriosis. Gynecol Endocrinol. 2011 Oct 17.