Prof. Jean Calleja Agius

Prof. Jean Calleja Agius

Prof. Jean Calleja Agius

 M.D.(Melit.),Ph.D.(Lond.),M.R.C.O.G.(Lond.),F.R.C.P.I.(Dublin),M.Sc.(Clinical Embryology)(Leeds)

Associate Professor

Biomedical Sciences Building
University of Malta
Professor Jean Calleja-Agius graduated as a Doctor of Medicine and Surgery from the University of Malta in 1999. She further specialised in Obstetrics and Gynaecology, both locally and at University College London Hospital (UCLH). She obtained her Memberships of the Royal College of Obstetricians and Gynaecologists and of the Royal College of Physicians of Ireland, on her first attempt in 2005.
From an early stage in her career, Professor Calleja-Agius showed a keen interest in research and teaching on all aspects of anatomy, particularly embryology and reproductive sciences. She was appointed as Assistant Lecturer in 2000, and since then has been teaching medical students, post-graduate trainees and other health professionals. She organised the first Advanced Life Support in Obstetrics (ALSO) UK in Malta in July 2011 for training obstetricians and midwives. She obtained a distinction in her MSc in Clinical Embryology at the University of Leeds, under the supervision of Prof Helen Picton.
She has numerous peer-reviewed research articles published in international high impact journals. She obtained her PhD (without corrections) at University College London (UCL) in February 2012. The title of her thesis is 'The Role of Pro- and Anti-inflammatory Cytokines in Early Pregnancy'. Her research involved investigation of the association between systemic and placental cytokines and miscarriages in human pregnancy. Her research supervisors were Professor Eric Jauniaux (UCL) and Dr Shanthi Muttukrishna (UCL/UCC), and the PhD examiners were Prof Lesley Regan from Imperial College (London) and Prof Siobhan Quenby from University of Warwick, who are all world authorities in the field of miscarriages and pregnancy complications.
The current research interests of Prof Calleja-Agius are embryology and reproductive medicine, particularly recurrent miscarriages and infertility.

2012: Best Abstract, 15th ISGE Congress, Florence
2010: Best Abstract in Under-34 Competition, 14th ISGE Congress,
2009: Green Armytage Travel Bursary (RCOG)
2008: Overseas Fund Travel Award (RCOG)
2007: Travel Award for the 31st British International Congress of
Obstetrics and Gynaecology
2006: Ethicon Travel Award (RCOG)
2005: Chancellor's Award (UOM)
2003: Best Oral Presentation 5th Maltese Medical School
  • Obstetrics and Gynaecology
  • Human embryology
  • Feto-placental Unit
  • Cytokines and inflammation
  • Infertility
  • Reproductive Immunology
  • Menopause
  • ANA1024 - Pelvic Anatomy
  • ANA1101 - Introduction to Anatomy for Dental Students
  • MDS1004 - Cardiovascular System
  • MDS1012 - Musculoskeletal System
  • MDS1013 - Organisation of the Body
  • MDS1014 - Renal System
  • MDS1026 - Molecular Biology and Genetics
  • MDS1029 - Reproduction
  • MDS2029 - Integrated Biomedical Sciences
  • MDS2031 - Gastrointestinal System
  • MDS2032 - Nervous System 1
  • MDS2033 - Nervous System 2
  • MID5000 - Normal Childbirth - Evidence and Debate
  • MID5001 - Advancing Midwifery Practice
  • RAD5237 - Anatomy and Embryology for Obstetric and Gynaecological Ultrasound
  • SUR5100 - Applied Surgical Anatomy and Physiology
Other Publications:
Calleja-Agius J, Jauniaux E, Muttukrishna S. Placental Villous Expression of TNFα
and IL-10 and Effect of Oxygen Tension in Euploid Early Pregnancy Failure. American
Journal of Reproductive Immunology. 2012 Jun; 67(6):515-25. Epub 2012 Jan 16

Calleja-Agius J, Jauniaux E, Pizzey AR, Muttukrishna S. Investigation of systemic
inflammatory response in first trimester pregnancy failure. Human Reproduction.
2012 Feb;27(2):349-57.

Calleja-Agius J, Jauniaux E, Muttukrishna S. Inflammatory cytokines in maternal
circulation and placenta of chromosomally abnormal first trimester miscarriages.
Clincal and Developmental Immunology. 2012;2012:175041.

Calleja-Agius J, Mallia P, Sapiano K, Schembri-Wismayer P. A review of the
management of intersex. Neonatal Network. 2012 Mar-Apr;31(2):97-103.

Portelli M, Pollacco J, Sacco K, Schembri-Wismayer P, Calleja-Agius J. Endometrial
seedlings. A survival instinct? Immunomodulation and its role in the
pathophysiology of endometriosis. Minerva Ginecologica. 2011 Dec;63(6):563-70.

Sacco K, Portelli M, Pollacco J, Schembri-Wismayer P, Calleja-Agius J. The role of
prostaglandin E(2) in endometriosis. Gynecol Endocrinol. 2011 Oct 17.

Calleja-Agius J, Brincat MP. Urogenital Atrophy Climacteric 2009; April 22: 1-7

Calleja-Agius J, Brincat MP. Recurrent miscarriages: What is the role of cytokines?
Gynecol Endocrinol. 2008 Dec; 24(12):663-8

Calleja-Agius J. Vaginal bleeding in the first trimester British Journal of
Midwifery 2008 Oct; 16 (10):656-670

Calleja-Agius J. Pre-conception care: essential advice for women British Journal of
Midwifery 2009 Jan; 17 (1):38-44

Calleja-Agius J, Custo R, Brincat MP, Calleja N. Placental
abruption and placenta praevia - a review. European Clinics in Obstetrics and
Gynaecology 2006; 2(3):121-7

Calleja-Agius J, Muscat-Baron Y, Brincat MP. Skin ageing. Menopause International

Calleja-Agius J, Muscat Baron Y, Brincat MP.The Skin, Carotid and Intervertebral
Disc-Making the Connection. Climacteric 2007, 10 (Suppl 2):1-5