Prof. Joseph Borg

Prof. Joseph Borg

Prof. Joseph Borg



Room 26
Block A, Level 1
Mater Dei Hospital
  +356 2340 1145
Joseph initially undertook the studies of applied biomedical science in the former Institute of Health Care, now Faculty of Health Sciences, University of Malta and subsequently followed specialised training in Molecular Genetics and Haematology. His research career began in 2004 when he formally joined the Laboratory of Molecular Genetics, Department of Physiology and Biochemistry (University of Malta) as an MSc student and participated in the final stages of the GEOPARKINSON project, an FP5 EU-funded project (QLK4-CT-1999-01133). In 2006, Joseph enrolled as a research assistant on an FP6 EU-funded project – Infrastructure for Thalassaemia Research Network (ITHANET RI-2004-026539) that started his career in experimental haematology and haemoglobin genetics. Subsequent work unveiled the molecular genetics of the HPFH KLF1-related condition (OMIM 613566) and established KLF1 as a novel quantitative trait locus for HbF (HBFQTL6). He has now published over a 100 publications that include both conference and peer-reviewed articles. His highest accolades include two high impact first-author publications in Nature Genetics, EMBO J, Haematologica, Human Mutation and Pharmacogenomics.

Joseph's current research interests as an academic with the Department of Applied Biomedical Science continue to focus on the molecular genetics of developmental globin gene switching and control. Together with his Borg Group he conducts extensive research on KLF1 erythroid-specific transcription factor, utilising both genomic (DNA-based) and transcriptomic (RNA-based) approaches in in-vitro (cell cultures) and in-vivo (clinical patients) models.

He is now also a member of the Analysis Working Group at the Nasa Gene Lab, USA run by Afshin Behesti and the ESA Space Omics Topical Team, studying amongst others the effects of spaceflight on erythropoiesis for both astronauts living on board the ISS and other missions and a range of mouse model organisms sent to space and back. This work is also done in collaboration with Christopher Mason at the Institute for Computational Biomedicine, Weill Cornell Medicine, USA.
  • Genetics
  • Cell Biology
  • Erythropoiesis
  • Molecular Biology
  • Pharmacogenomics
  • Whole Genome Sequencing
  • Impact of genetic engineering
  • ABS5001 - Advanced Genetics and Molecular Techniques
  • ABS5002 - Research, Data Analysis and Interpretation
  • FEH5019 - Fundamental Studies in Nutrition and Dietetics
  • MLS1001 - Introduction to Biomedical Biochemistry and Cell Biology
  • MLS2018 - Haematopathology
  • MLS2019 - Diagnostic Laboratory Haematology
  • MLS4006 - Applied Clinical Biochemistry
  • PHB5030 - Molecular Biology and Genetics

BORG Joseph

ResearchGate: Date of birth: 27th July 1982

Nationality: Maltese URL for website: and


2007-2010 PhD Faculty of Medicine & Surgery, University of Malta, Malta

2004-2007 MSc Faculty of Medicine & Surgery, University of Malta, Malta

2000-2004 B.Sc(Hons) Faculty of Health Sciences, University of Malta, Malta


2020 – present Investigator – Multiomics and Systems Biology (Analysis Working Group) NASA GeneLab

2015 – present Associate Professor, Department of Applied Biomedical Science, University of Malta, Malta

2013 – present PI, Centre for Molecular Medicine and Biobanking, University of Malta, Malta


2013 – 2015 Senior Lecturer, Department of Applied Biomedical Science, University of Malta, Malta

2010 – 2011 Lecturer, Department of Applied Biomedical Science, University of Malta, Malta


2021 – present Topical Team member with European Space Agency space omics team

2011 – 2013 Post-doc (EMBO Long-term fellow [2011, Applications 1633, Awarded 268, Success rate 16%), Department of Cell
Biology, Erasmus MC, Rotterdam, The Netherlands

2011 Visiting Professor, University of Cagliari, Regional Hospital for Microcythemia, Cagliari, Sardegna

2009 – 2010 Laboratory Officer II, Faculty of Medicine & Surgery, University of Malta, Malta

1999 – 2009 Veterinary Assistant, Drs Med Vet Annette & Louis Borg, B’Kara, Malta


2021 Young Researcher Award, National STEM Awards, Villa Bighi, Kalkara, Malta

2021 STEM Ambassador Award, National STEM Awards, Villa Bighi, Kalkara, Malta

2020 Honour Award in recognition of the support towards the cause of rare diseases by the National Alliance for Rare Diseases
Support, Malta

2019 – 2022 Research Excellence Award, University of Malta, Malta

2011 – 2013 EMBO Long-term fellowship (ALTF 71-2011) – The first ever Maltese scientist to receive this award and progress with
independent research

2008 – 2009 EMBO Short-term fellowship (ASTF 383.00-2008)

2008 HUGO Award, Human Mutation Detection, Rotterdam, The Netherlands

2007 PhD Scholarship Award, Malta Government, Malta

2006 First Prize - oral presentation at the 6th Malta Medical School Conference