Apart from the historical structures, the Argotti Botanic Gardens & Resource Centre is made up of different sections, each offering a unique combination of botanical specimens.

The most important historical structures dating back to the eighteenth century consisted of the Nymphaeum and the Summer Villa. The Nymphaeum was once wholly lined with a decorative motif using black obsidian and white marble pebbles, red coral and calcite crystals. The coat of arms of bailiff Ignatius de Argote y Guzman from which the garden name derived is on the ceiling.

The old summer house of Bailiff de Argote was recently renovated and converted into an exhibition hall. A newly built structure is a modern purpose-built herbarium housing the old dried plant collections together with a small laboratory.

The garden houses different plant collections in specialised areas, as well as plots that represent different plant families. A section is also dedicated to Mediterranean Flora with indigenous and endemic plants present.

Some plant collections are also housed in the three greenhouses, and these predominantly contain collections of cacti and succulents.  Other recently refurbished garden features include the Japanese, Water pond, Shade, Semi-arid, Cactus, Euphorbia and Opuntia areas.