Azzopardi studied History at the University of Malta (2007–2010), graduating with a First-Class Honours degree. Her dissertation focused on the Grand Harbour Extension Project of the 1860s. She then pursued a Master’s degree in Global and Imperial History at the University of Oxford (2011–2012), where she explored British imperial benevolence in Malta during the 1930s, particularly in relation to de-Italianisation, Anglicisation, and the loss of self-government. Throughout her academic journey, her research has primarily centered on Maltese history during the British period and the broader framework of Global History.
She later completed a Ph.D. in History at the University of Malta, with her research examining women's emancipation in Malta from the 1960s to the late 1980s. Her work explored key developments in education, the economy, politics, and social activism.
An active member of the Malta Historical Society (MHS) since 2015 (till 2023), Azzopardi played a central role in organising public lectures and overseeing major events such as the biennial History Week (2015, 2017, 2019) and the biennial Publication Awards (2018, 2020). She also co-edited The Proceedings of History Week 2015 (2018) and Storja (2023). Currently, she serves as vice-president of the Malta University Historical Society (MUHS).
Azzopardi has published extensively in Melita Historica and in other local and international academic publications. Her most recent works include chapters in two separate books: 'A Mediterranean Island at a Crossroads: 1950s Malta in Empire' and 'Women at Work: Female Labour in Post-WWII Malta.' She is also a regular guest on radio and TV programmes, where she discusses various historical themes related to her research interests.
Beyond academia, Azzopardi is a co-founder and the current chairperson of Għawdix, a Gozo-based environmental NGO.
SIMONE AZZOPARDI AND EMANUEL BUTTIGIEG, 2020. L-Università ta’ Malta: A History. In: BY KEITH SCIBERRAS, EMANUEL BUTTIGIEG, MARK-ANTHONY FALZON, DOMINIC FENECH, GILLIAN M. MARTIN, ed, The University of Malta: Legacies and Bearings. Malta: University of Malta, .
The Grand Harbour Extension Project: Economic and Political Implications for British Malta, 1858-1870s. 2018. In: CARMEL VASSALLO AND SIMON MERCIECA, ed, The Port of Malta. Malta: .
SIMONE AZZOPARDI AND EMANUEL BUTTIGIEG, 2018. Colonialism in the Mirror: An Analysis of Representations of Colonialism in School History Textbooks in Malta before and after Independence (1964). In: DR KAREL VAN NIEUWENHUYSE AND DR JOAQUIM PIRES VALENTIM, ed, International Review of History Education. USA: Information Age Publishing, pp. 199.
SIMONE AZZOPARDI, JONATHAN BORG AND DAVID MALLIA, ed, 2018. Proceedings of History Week 2015. Malta: Malta Historical Society.
BUTTIGIEG, E.A.A.,SIMONE, 2017. Outlines of Maltese history and Ġrajjet Malta : an analysis of representations of colonialism in Maltese History textbooks. Melita Historica, 17(1),.
SIMONE AZZOPARDI, 2017. Review of Tamara van Kessel, Foreign Cultural Policy in the Interbellum: The Italian Dante Alighieri Society and the British Council Contesting in the Mediterranean (2016). Journal of Mediterranean Studies, 26(2),.
SIMONE AZZOPARDI, 2016. Imperial Policy in Malta, 1934-9: Britain's Need for Benevolent Despotism. Melita HIstorica. Malta: Malta Historical Society, .
SIMONE AZZOPARDI AND EMANUEL BUTTIGIEG, 2015. Symbiotics of History and Social Psychology: Understanding Social Representations of History in Europe.
