Marine litter, specifically plastics at sea, represents one of the most studied emerging marine pollutants. The existing scientific literature lists the effects that plastics at sea (belonging to the 3 size categories of mega-, macro- and micro-plastics) can have on a global scale on a variety of marine ecosystems and species that inhabit them. The promotion of harmonised/standardised monitoring and the development of validated high resolution dispersion models have been recognised as effective tools to inform management measures (i.e. mitigation). TecMAReco, funded through the INTERREG VI-A Italia-Malta Programme and co-financed by the European Union, takes advantage of knowledge and tools already acquired and tested through previous cooperation projects, to create these two salient management cornerstones which are useful when dealing with marine systems in transitional areas (e.g. Italy and Malta).