Prof. Janet Mifsud

Prof. Janet Mifsud

Prof. Janet Mifsud



Faculty of Medicine & Surgery
Clinical Pharmacology & Therapeutics
University of Malta
  +356 2340 2582
Prof Janet Mifsud obtained her PhD in UK in 1995 on the pharmacology of chiral antiepileptic drugs. Her research activities in epilepsy are undertaken with colleagues in Mater Dei Hospital, University College London and numerous other international epilepsy centres. She has published extensively and has been appointed on the organising and scientific committees of several international epilepsy conferences. Prof Mifsud was Secretary General for the European Epilepsy Academy and also Vice-President for the International Bureau for Epilepsy; and she is presently member, Joint Task Force, European Epilepsy Research and Advocacy. She is an advisor, Caritas Malta Epilepsy Association. She was officially awarded the title of Epilepsy Ambassador by the International League Against epilepsy and International Bureau of Epilepsy in 2019.

Prof Mifsud co-ordinates pharmacology study units offered at the University of Malta for Faculties of Medicine and Surgery; Health Sciences; Science; Education; and Dental Surgery. She also co-ordinates a Pharmacotoxicology Course and the preparation of final year MD students for the UK Prescribing Skills Assessment. She was elected Fellow of the British Pharmacological Society in 2017 and in 2019 was invited as a Review Science Editor for the British Journal of Clinical Pharmacology.

She is involved in several EU and internationally funded projects in FP7. H2020, Ersamus+ and IMI. She has also been invited to act as external expert evaluator for scientific projects for several international and European wide panels. Prof Mifsud is national expert on the Pharmacokinetics Working Group (PKWP) in European Medicines Agency.

On a national level, she was the first Commissioner, National Commission for the Promotion of Equality (NCPE) and was for several years a member of the Public Service Commission. She is also Board Member, New Hope Services for Drug Rehabilitation, Caritas Malta; Centre for Freedom from Addiction, President's Foundation for the Wellbeing of Society; and Fund for Voluntary Organisations, Malta Community Chest Fund.
  • Pharmacokinetics, Pharmacometrics and Pharmacogenetics
  • Pharmacology of drugs used in chronic neurological disorders specifically anti-epileptic drugs
  • Pharmacotoxicology
  • Abuse and misuse of over the counter drugs and Drug Doping in sports
  • Stigma and inclusion in epilepsy
  • Ethical issues in health care and pharmacology
  • Gender and science

SPECCHIO, N., FERRETTI, A. and MIFSUD, J., 2021. Identification of Geographic Sites Studying Photosensitivity. . In: KASTELEIJN-NOLST TRENITE D., ed, The Importance of Photosensitivity for Epilepsy. 1st edn. Cham, Switzerland: Springer, pp. 323-335.

MIFSUD DE GRAY , J., 2020. Novel considerations on drug safety in epilepsy. Expert Opinion on Drug Safety, , pp. 1-3.

MIFSUD, J. and GAVRILOVICI, C., 2019. Big Data in Healthcare and the Life Sciences
. In: Z. KOPORC, ed, Ethics and Integrity in Health and Life Sciences Research. Volume 4 edn. London: Emerald Publishing, pp. 63-68.

PITKÄNEN, A., HENSHAL, D., CROSS, J., GUERRINI, R., JOZWIAK, S., KOKAIA, M., SIMONATO, M., SISODIYA, S. and MIFSUD, J., 2019. Advancing research toward faster diagnosis, better treatment, and end of stigma in epilepsy. Epilepsia, 60, pp. 1281-1292.

ZELANO, J., KLECKI, J., CHRISTENSEN, J., TOMSON, T., MALMGREN, K. and ESBACE, C.C., 2019. The provision of epilepsy care across Europe 2017: A 17-year follow-up survey. Epilepsia Open, 15(4), pp. 144-154.

MIFSUD, J., 2018. Administering epilepsy rescue medication to children: Why and why not? European Journal of Paediatric Neurology, 22(1), pp. 6.

MIFSUD, J. and BRODIE, M., 2018. Lay epilepsy organizations: The key for research funding? Epilepsy and Behaviour, 81, pp. 123-124.

BRINKMAN, D.J., TICHELAAR, J., MOKKINK, L.B., CHRISTIAENS, T., LIKIC, R., MACIULAITIS, R., COSTA, J., SANZ, E.J., MAXWELL, S.R., RICHIR, M.C., MIFSUD, J. and ET, A., 2017. Key learning outcomes for clinical pharmacology and therapeutics education in Europe: A modified Delphi study. Clinical Pharmacology & Therapeutics, December.

CHNEIWEISS, H., HIRSCH, F., MONTOLIU, L., MALLER, M., FENET, S., ABECASSIS, M., MERCHANT, J., BAERTSCHI, B., BOTBOL-BAUM, M., MIFSUD, J. and HOUGHTON, J., 2017. Fostering responsible research with genome editing technologies: a European perspective. Transgenic research, 26(5), pp. 709-713.

MAGRI, D. and MIFSUD, J., 2017. COST special issue. Malta Chamber of Scientists.

MIFSUD, J., 2017. Medicine Adherence in the aging population - the role of pharmacokinetics and pharmacodynamics. In: E. COSTA, A. GIARDINI and A. MONACO, eds, Adherence to Medical plans for Active and healthy Aging. 1sr edn. New York149-164: Nova Science Publishers, .

MIFSUD, M., JICKELLS, S., MIFSUD J and WOLFF, K., 2017. EcstasyTablets: Batch Matching for Forensic Drug Intelligence Purposes in Malta. Detection of Drug Misuse: Biomarkers, Analytical Advances and Interpretation, , pp. 288.

O'SULLIVAN, J., BLAKE, K., BERNTGEN, M.L., SALMONSON, T., MIFSUD, J. and WELINK, J., 2017. Overview of the European Medicines Agency's Development of Product Specific Bioequivalence Guidelines. Clinical Pharmacology & Therapeutics, .

BAULAC, M., BOER, H., ELGER, C., GLYNN, M., KALVINNINEN, R., LITTLE, A., MIFSUD, J., PERUCCA, E., PITKANEN, A. and RYVLIN, P., 2015. Epilepsy priorities in Europe: A report of the ILAE/IBE Epilepsy Advocacy Europe Task Force. Epilepsia, 56(11), pp. 1687-1695.

MIFSUD, J. and MALIEPAARD, M., 2015. Pharmacokinetics and Pharmacogenetics: Bringing the Magic Bullet Closer to Reality. Preventive and Predictive Genetics: Towards Personalised Medicine. Springer, Cham, pp. 91-107.

SCERRI, A.M., SOLER, D., CALLEJA, N. and MIFSUD, J., 2015. Prescribing Aeds In A Pediatric Neurology Clinic In Malta. Epilepsia, 56, pp. 209-210.

SCIBERRAS, J.N., GALLOWAY, S.D.R., FENECH, A., GRECH, G., FARRUGIA, C., DUCA, D. and MIFSUD, J., 2015. The effect of turmeric (Curcumin) supplementation on cytokine and inflammatory marker responses following 2 hours of endurance cycling. Journal of the International Society of Sports Nutrition, 12(1), pp. 5.

ARZIMANOGLOU, A., LAGAE, L., CROSS, J.H., BEGHI, E., MIFSUD, J., BENNETT, C., SCHMIDT, D., WAIT, S. and HARVEY, G., 2014. The administration of rescue medication to children with prolonged acute convulsive seizures in a non-hospital setting: an exploratory survey of healthcare professionals’ perspectives. European journal of pediatrics, 173(6), pp. 773-779.

BELLIZZI, M., CASSAR, K. and MIFSUD, J., 2014. Pain Management In Lower Limb Major Amputation. Basic & Clinical Pharmacology & Toxicology, 115, pp. 78-79.

CARDONA, P. and MIFSUD, J., 2014. Doping in sport: assessing knowledge among health care professionals. Basic & Clinical Pharmacology & Toxicology, 115, pp. 354.

MIFSUD, J. and DIMECH, V., 2014. Using The Stigma Scale Of Epilepsy (sse) To Assess Effectiveness Of An Epilepsy Inservice Programme For Educators. Epilepsia, 55, pp. 125.

MIFSUD, J., 2014. Gender differences in epilepsy: perceived or real? Journal of the Malta College of Pharmacy Practice, , pp. 28.

VELLA, T. and MIFSUD, J., 2014. Interactions Between Valproate And Olanzapine/quetiapine In Bipolar Disorder. Basic & Clinical Pharmacology & Toxicology, 115, pp. 72.

CROSS, J.H., WAIT, S., ARZIMANOGLOU, A., BEGHI, E., BENNETT, C., LAGAE, L., MIFSUD, J., SCHMIDT, D. and HARVEY, G., 2013. Are we failing to provide adequate rescue medication to children at risk of prolonged convulsive seizures in schools? Archives of Disease in Childhood, , pp. archdischild-2013.

JETTE, N., ALI, A., AUSTIN, J.K., BIRBECK, G.L., DE BOER, H., BRAGA, P., CROSS, J.H., DUA, T., FERNANDES, P.T. and LORENZETTI, D.L., 2013. Stigma In Epilepsy-An International Perspective. Epilepsia, 54, pp. 12-13.

LAGAE, L., ARZIMANOGLOU, A., BEGHI, E., BENNETT, C., CROSS, H.J., MIFSUD, J., SCHMIDT, D., WAIT, S. and HARVEY, G., 2013. Guidelines on the management of prolonged acute convulsive seizures in out-of-hospital settings: a gap to be filled. European Journal of Paediatric Neurology, 17, pp. S74-S75.

LAPIRA, A., SAMMUT, N., SCERRI, C., CORDINA, G., MIFSUD, J., HARPER, J.C., SCERRI, R.S. and CASTILLO, N., 2013. National strategy for health research and innovation. Xjenza-Online, 2013, pp. 82.

MIFSUD, J. and BELLIA, C., 2013. COST: Matchmaking for Researchers. Xjenza-Online, 2013, pp. 75.

MIFSUD, J., VELLA, T. and ELLUL-MICALLEF, R., 2013. Antipsychotics And Aeds: Therapeutic Drug Monitoring In A Mental Health Care Setting. Epilepsia, 54, pp. 62-63.

WAIT, S., LAGAE, L., ARZIMANOGLOU, A., BEGHI, E., BENNETT, C., CROSS, J.H., MIFSUD, J., SCHMIDT, D. and HARVEY, G., 2013. The administration of rescue medication to children with prolonged acute convulsive seizures in the community: what happens in practice? European Journal of Paediatric Neurology, 17(1), pp. 14-23.

BAULAC, M., DE BOER, H., ELGER, C., GLYNN, M., KALVEINEN, R., LITTLE, A., MIFSUD, J., PERUCCA, E. and PITKäNEN, A., 2012. The written declaration on epilepsy: an important achievement for Europe and beyond. Seizure-European Journal of Epilepsy, 21(1), pp. 75-76.

MIFSUD, J., 2012. The effects of antiepileptic drugs in relation to dentistry. The Dental Probe - The Maltese Dental Journal, March(41), pp. 33-36.

MIFSUD, J. and SGHENDO, L.J., 2012. A novel chiral GC/MS method for the analysis of fluoxetine and norfluoxetine enantiomers in biological fluids. Journal of pharmacy & bioallied sciences, 4(3), pp. 236.

MIFSUD, J., 2011. Facing the Challenges: Malta. In: D. CHAPMAN, D. PANELLI, J. HANNA and T. JEFFS, eds, Sudden Unexpected Death in Epilepsy: continuing the global conversation. Australia: Epilepsy Australia Ltd, pp. 123-124.

MIFSUD, J., 2011. Abuse of OTC and Prescribed Drugs: Popping Pills for Thrills. Journal of the Malta College of Pharmacy, 17, pp. 16-20.

MIFSUD, J., ATTARD, D. and ATTARD, L., 2011. Drug doping in sports: an overview and recommendations for the Maltese context. Malta Medical Journal, 23(1),.

PETR, P., MIFSUD, J., 2011. Clinical Pharmacology in Malta. Klinická farmakologie a farmacie, 25(3),.

MIFSUD, J., 2010. Phenobarbital and Other Barbiturates. Atlas of Epilepsies. Springer, pp. 1807-1812.

MIFSUD, J., 2010. Primidone. Atlas of Epilepsies. Springer, pp. 1825-1827.

BAULAC, M. and PITKANEN, A., 2009. Research priorities in epilepsy for the next decade: a representative view of the European scientific community: summary of the ILAE Epilepsy Research Workshop, Brussels, 17-18 January 2008. Epilepsia, 50(3), pp. 571-578.

MIFSUD, J., CAMILLERI, T. and GALEA, R., 2009. Pregnancy And Birth Outcomes In Females Of Child Bearing Age In Malta. Epilepsia, 50, pp. 72.

MIFSUD, J., DARMANIN, E.R., CORDINA, M., FENECH, A. and BUHAGIAR, A., 2009. Health Complaints And Use Of Medicines Among Adolescents In Malta. Basic & Clinical Pharmacology & Toxicology, 105, pp. 134.

MILLERSHIP, J.S., MIFSUD, J., GALEA, D., MCROBERTS, W.C. and HAMILTON, J., 2005. Chiral aspects of the human metabolism of ethosuximide. Biopharmaceutics & drug disposition, 26(6), pp. 225-232.

SGHENDO, L., MIFSUD, J., ELLUL-MICALLEF, R., PORTELLI, J. and MILLERSHIP, J.S., 2002. A sensitive gas chromatographic/mass spectrometric method for the resolution and quantification of ethosuximide enantiomers in biological fluids. Journal of Chromatography B, 772(2), pp. 307-315.

MILLERSHIP, J.S., MIFSUD, J. and COLLIER, P.S., 1993. The metabolism of ethosuximide. European journal of drug metabolism and pharmacokinetics, 18(4), pp. 349-353.

  • CHE1012 - Principles of Chemistry and Biochemistry related to Care
  • CPH1710 - Pharmacological Principles in Dentistry
  • CPH1800 - Basic Principles of General Pharmacology in Food Science
  • CPH1902 - Overview of Drug Classes and Function
  • CPH1905 - Pharmacokinetics and Pharmacodynamics 1
  • CPH1908 - Principles of Pharmacotherapeutics
  • CPH1909 - Pharmacology Seminars 1
  • CPH2011 - Drugs used in Disorders of the Nervous and Cardiovascular Systems
  • CPH2110 - Introduction to Molecular and Clinical Pharmacology
  • CPH2301 - Introduction to Pharmacology for Applied Biomedical Science Students
  • CPH2402 - Pharmacology for Allied Health Care Professionals
  • CPH2404 - Pharmacology for Midwifery Students
  • CPH3010 - Drugs used in Asthma, COPD and Epilepsy: Applications of Pharmacokinetics
  • CPH3601 - Introduction to Pharmacology for Chemistry Students
  • CPH3700 - Theory and Applications of Molecular Pharmacology
  • CPH4120 - Applied Molecular and Clinical Pharmacology
  • CPH4500 - Introduction to Pharmacology for Biology and Chemistry Students
  • CPH4600 - Pharmacology for Podiatry Students
  • CPH5401 - Fundamentals of Pharmacotoxicology: Principles, Classification and Toxicokinetics
  • CPH5402 - Mechanisms of Drug Toxicity: Molecular, Cellular and Pathological
  • CPH5403 - Clinical Toxicology and Management of Poisoning of Commonly Used Pharmaceuticals 1
  • MDS1013 - Organisation of the Body
  • MDS1014 - Renal System
  • MDS2009 - Pharmacology
  • MDS2031 - Gastrointestinal System
  • MDS4013 - Neurology and Ophthalmology
  • MDS4033 - Essential Core Competences
  • RAD3330 - Pharmacology and Radiopharmacy for Radiographers
Research work in progress

- Pharmacokinetics and pharmacogenetics of drugs used in chronic neurological disorders
- OTC drug use and misuse and drug doping in sports
- Neurotoxicology and poisoning
- Stigma and educational inclusion in epilepsy

Involvement in projects and ongoing collaborations

- Member of the Scientific Advisory Board, IMI project NeuroDeRixk Neurotoxicity DeRisking in
Preclinical Drug Discovery IMI-JU 821528 2019-2023
- Consortium Parter, H2020 GENDER ACTION GENDer equality in the ERA Community To Innovate
policy implementatiON. Coordination and Support Action SwafS-19-216 2017-2021
- Chair, Dissemination board and Ethics Board FP7 DESIRE Development and Epilepsy Strategies
for innovative research to improve Diagnosis, Prevention and Treatment in children with
Difficult to Treat Epilepsy (Health-F2-602531-2013)(2013-2018)
- Workpackage leader Parter, Erasmus+, IT-based international diploma and professional
certificates in clinical toxicology (ITCT)(KA2 561915-EPP-1-2015-1-EG-EPPKA2-CBHE-JP)(2015-
- Workpackage leader Partner, LLP Erasmus Network, Science for Prevention Academic Network
(SPAN) (2013-2015)
- Partner, Leonardo Da Vinci LLP EU project on disability education (2009-2012)
- Chair, Dissemination board EU funded FP6 project EPICURE: Functional Genomics and
Neurobiology of Epilepsy: A Basis for New Therapeutic Strategies (LSH-037315). (2004-2009)
- UNESCO grant on learning impairment in epilepsy;
- Co-coordinator Grundtvig project. Curricular Education for Professionals Allied to Medicine
(PAMs) in Epilepsy 2006-2011.
- Co-ordinator of a UNESCO funded project on Gender Gap in science and technology in Malta,
- Co-ordinator of an EU Youth Grant - Epilepsy Youth in Europe, 2003

- Epilepsy Ambassador, International League Against Epilepsy and International Bureau of
Epilepsy, 2019
- Elected Fellow of the British Pharmacological Society, 2017
- Pektur award, Commission for Persons with Disability, 2017
- Italo Maltese award to La Sapienza University Rome Italy, 2009
- Visiting fellow US Fulbright scholarship to the University of Minnesota, 2007
- Pektur award, Commission for Persons with Disability, 2001
- DAAD grant, Bethel Epilepsy Clinic, Germany, 1999