The University today has fourteen Faculties: Built Environment; Arts; Dental Surgery; Economics, Management & Accountancy; Education; Engineering; Health Sciences; Information & Communication Technology; Laws; Media & Knowledge Sciences; Medicine & Surgery; Science, and Social Wellbeing and Theology.

A number of interdisciplinary Institutes and Centres have been set up in various fields. The Institutes include Anglo-Italian Studies; Baroque Studies; Confucius; Digital Games; Earth Systems; European Studies; Islands & Small States; Linguistics; Maltese Studies; Public Administration & Management; Physical Education & Sport; Sustainable Development; Sustainable Energy; Tourism, Travel & Culture; Mediterranean Institute, Edward de Bono Institute for the Design & Development of Thinking, and the Mediterranean Academy of Diplomatic Studies.

The Centres comprise: Centre for Biomedical Cybernetics; Centre for English-Language Proficiency; Centre for Entrepreneurship and Business Incubation; Centre for Environmental Education & Research; Centre for Labour Studies; Centre for Literacy; Euro-Mediterranean Centre for Educational Research; Euro-Mediterranean Centre on Insular Coastal Dynamics; European Centre of Educational Resilience & Socio-Emotional Health; European Centre for Gerontology and the International Ocean Institute - Malta Operational Centre.

The University of Malta has also set up a School of Performing Arts.

The campus is home to the IMO International Maritime Law Institute (IMLI).

The public response to the University of the Third Age has been very encouraging with membership constantly on the increase and all activities being well attended.